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➤Papers-Ganoderma Proteins

1. Wei-Jyun Hua, Wei-Lun Hwang, Hsin Yeh, Zhi-Hu Lin, Wei-Hung Hsu, Tung-Yi Lin*. Ganoderma microsporum immunomodulatory protein combined with KRAS^G12C inhibitor impedes intracellular AKT/ERK network to suppress lung cancer cells with KRAS mutation. International Journal of Biological Macromolecules. 2024. 259:129291. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
2. Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Ai-Jung Tseng, Li-Chen Huang, Wei-Lun Qiu, Tsung-Hsi Tu, Ding-Han Wang, Wei-Hung Hsu, Wei-Lun Hwang, Tung-Yi Lin*. Ganoderma microsporum immunomodulatory protein as an extracellular epidermal growth factor receptor (EGFR) degrader for suppressing EGFR-positive lung cancer cells. Cancer Letters. 2023. 578: 216458. (SCI, IF: 9.7, Rank: 14.1%) Corresponding author
3. Hung-Chih Lo, Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Li-Chen Huang, Yi-Ru Ciou, Runcheng Ruan, Kai-Fan Lin, Ai-Jung Tseng, Alexander T.H. Wu, Wei-Hung Hsu, Chi-Hong Chao, Tung-Yi Lin*. GMI, a Ganoderma microsporum protein, abolishes focal adhesion network to reduce cell migration and metastasis of lung cancer. Life Sciences. 2023. 335: 122255. (SCI, IF: 6.1, Rank: 12.2%) Corresponding author
4. Zhi-Hu Lin, Hsin Yeh, Hung-Chih Lo, Wei-Jyun Hua, Ming-Yang Ni, Li-Kai Wang, Ting-Ting Chang, Muh-Hwa Yang, Tung-Yi Lin*. GMI, a fungal immunomodulatory protein, ameliorates SARS-CoV-2 envelope protein-induced inflammation in macrophages via inhibition of MAPK pathway. International Journal of Biological Macromolecules. 2023. 241: 124648. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
5. Ai-Jung Tseng, Tsung-Hsi Tu, Wei-Jyun Hua, Hsin Yeh, Ching-Jung Chen, Zhi-Hu Lin, Wei-Hung Hsu, Ying-Lan Chen, Chuan-Chih Hsu, Tung-Yi Lin*. GMI, Ganoderma microsporum protein, suppresses cell mobility and increases temozolomide sensitivity through induction of Slug degradation in glioblastoma multiforme cells. International Journal of Biological Macromolecules. 2022. 219: 940-948. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
6. Ha Phan Thanh Ho, Di Ngoc KhaVo, Tung-Yi Lin, Jo-Ning Hung, Ya-Hui Chiu, Ming-Han Tsai*. Ganoderma microsporum immunomodulatory protein acts as a multifunctional broad-spectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion. Biomedicine & Pharmacotherapy. 2022. 155:113766. (SCI, IF: 7.5, Rank: 8.3%) Third author
7. Hsin Yeh, Di Ngoc Kha Vo, Zhi-Hu Lin, Ha Phan Thanh Ho, Wei-Jyun Hua, Wei-Lun Qiu, Ming-Han Tsai, Tung-Yi Lin*. GMI, a protein from Ganoderma microsporum, induces ACE2 degradation to alleviate infection of SARS-CoV-2 Spike-pseudotyped virus. 2022. 103: 154215. (SCI, IF: 7.9, Rank: 3.6%) Corresponding author
8. Tung-Yi Lin*, Wei-Jyun Hua, Hsin Yeh, Ai-Jung Tseng. Functional proteomic analysis reveals that fungal immunomodulatory protein reduced expressions of heat shock proteins correlates to apoptosis in lung cancer cells. 2021. 80:153384. (SCI, IF: 7.9, Rank: 3.6%) First & Corresponding author
9. Tung-Yi Lin, Hsien-Yeh Hsu, Wei-Hsuan Sun, Tsung-Han Wu and Shu-Ming Tsao. Induction of Cbl-dependent epidermal growth factor receptor degradation in Ling Zhi-8 suppressed lung cancer. International Journal of Cancer. 2017. 140(11):2596-2607. (SCI, IF: 6.4, Rank: 21.6%) First author
10. Tung-Yi Lin and Hsien-Yeh Hsu. Ling Zhi-8 reduces lung cancer mobility and metastasis through disruption of focal adhesion and induction of MDM2-mediated Slug degradation. Cancer Letters. 2016. 375(2):340-348. (SCI, IF: 9.7, Rank: 14.1%) First author
11. Hsien-Yeh Hsu*, Tung-Yi Lin*, Ruey-Shyang Hseu, and Ching-Tsan Huang. Ling Zhi immuno-modulation protein, LZ-8 induction of interleukin-1 expression in human monocytes via pertussis toxin-sensitive G protein-mediated protein kinase pathway. Adaptive Medicine. 2014. 6(2): 63-72. Co-first author
12. Hsien-Yeh Hsu, Yen-Chou Kuan, Tung-Yi Lin, Shu-Ming Tsao, Jason Hsu, Li-Juan Ma, and Fuu Sheu. Reishi protein LZ-8 induces FOXP3⁺ Treg expansion via a CD45-dependent signaling pathway and alleviates acute intestinal inflammation in mice. Evid Based Complement Alternat Med. 2013. 2013:513542. (SCI, IF: 2.650, Rank: 53.3%)
13. Chien-Ting Wu*, Tung-Yi Lin*, Hsien-Yeh Hsu, Fuu Sheu, Chau-Mei Ho and Edmund I.-T.Chen. Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway. Carcinogenesis. 2011. 32(12):1890-6. (SCI, IF: 4.7, Rank: 35.3%) Co-first author

➤Papers-Ganoderma Polysaccharides

1. Hung-Chih Lo, Tzu-En Lin, Che-Yu Lin, Wei-Hao Wang, Yu-Chen Chen, Pei-Hsien Tsai, Jung-Chen Su, Mei-Kuang Lu, Wei-Hung Hsu, Tung-Yi Lin*. Targeting TGFβ receptor-mediated snail and twist: WSG, a polysaccharide from Ganoderma lucidum, and it-based dissolvable microneedle patch suppress melanoma cells. Carbohydrate Polymers. 2024. 341:122298. (SCI, IF: 10.7, Rank: 1.7%) Corresponding author
2. Wei-Lun Qiu, Hung-Chih Lo, Mei-Kuang Lu, Tung-Yi Lin*. Significance of culture period on the physiochemistry and anti-cancer potentials of polysaccharides from mycelia of Ganoderma lucidum. International Journal of Biological Macromolecules. 2023. 242: 125181. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
3. Wei-Lun Qiu, Wei-Hung Hsu, Shu-Ming Tsao, Ai-Jung Tseng, Zhi-Hu Lin, Wei-Jyun Hua, Hsin Yeh, Tzu-En Lin, Chien-Chang Chen, Li-Sheng Chen, Tung-Yi Lin*. WSG, a glucose-rich polysaccharide from Ganoderma lucidum, combined with cisplatin potentiates inhibition of lung cancer in vitro and in vivo. 2021. 13:4353. (SCI, IF: 5.0, Rank: 18.6%) Corresponding author
4. Wei-Hung Hsu, Wei-Jyun Hua, Wei-Lun Qiu, Ai-Jung Tseng, Hsin-Chung Cheng, Tung-Yi Lin*. WSG, a glucose-enriched polysaccharide from Ganoderma lucidum, suppresses tongue cancer cells via inhibition of EGFR-mediated signaling and potentiates cisplatin-induced apoptosis. International Journal of Biological Macromolecules. 2021. 193:1201-1208. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
5. Wei-Hung Hsu, Wei-Lun Qiu, Shu-Ming Tsao, Ai-Jung Tseng, Mei-Kuang Lu, Wei-Jyun Hua, Hsin-Chung Cheng, Hsien-Yeh Hsu, Tung-Yi Lin*. Effects of WSG, a polysaccharide from Ganoderma lucidum, on suppressing cell growth and mobility of lung cancer. International Journal of Biological Macromolecules. 2020. 165:1604-1613. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
6. Shih-Fen Liao, Chi-Hui Liang, Ming-Yi Ho, Tsui-Ling Hsu, Tsung-I Tsai, Yves S.-Y. Hsieh, Chih-Ming Tsai, Shiou-Ting Li, Yang-Yu Cheng, Shu-Ming Tsao, Tung-Yi Lin, Zong-Yan Lin, Wen-Bin Yang, Chien-Tai Ren, Kuo-I Lin, Kay-Hooi Khoo, Chun-Hung Lin, Hsien-Yeh Hsu, Chung-Yi Wu, and Chi-Huey Wong. Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes. Proc Natl Acad Sci U S A. 2013. 110(34):13809-14. (SCI, IF: 11.1, Rank: 11.0%)

➤Papers-Antrodia cinnamomea Polysaccharides

1. Zhi-Hu Lin, Hung-Chih Lo, Chia-Chuan Chang, Mei-Kuang Lu*, Ai-Jung Tseng, Chi-Hsein Chao, Chi-Hong Chao, Tung-Yi Lin*. Sulfated polysaccharide from Antrodia cinnamomea mycelium cultured with zinc sulfate stimulates M1 polarization of macrophages through AKT/mTOR pathways. International Journal of Biological Macromolecules. 2024. 279: 135548. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author
2. Zhi-Hu Lin, Mei-Kuang Lu, Hung-Chih Lo, Chia-Chuan Chang, Ai-Jung Tseng, Chi-Hsein Chao, Tung-Yi Lin*. ZnF3, a sulfated polysaccharide from Antrodia cinnamomea, inhibits lung cancer cells via induction of apoptosis and activation of M1-like macrophage-induced cell death. International Journal of Biological Macromolecules. 2023. 238:124144. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
3. Tung-Yi Lin*, Mei-Kuang Lu, Ai-Jung Tseng, Chi-Hsein Chao. Effects of sterol-type elicitors on biochemical characterization of polysaccharides from Antrodia cinnamomea. International Journal of Biological Macromolecules. 2020. 162:1476-1483. (SCI, IF: 8.2, Rank: 5.8%) First & Corresponding author
4. Tung-Yi Lin*, Chia-Chuan Chang, Ai-Jung Tseng, Chi-Hsein Chao, Mei-Kuang Lu. Sodium thiosulfate enhances production of polysaccharides and anticancer activities of sulfated polysaccharides in Antrodia cinnamomea. Carbohydrate Polymers. 2019. 216:204-212. (SCI, IF: 11.2, Rank: 3.5%) First & Corresponding author
5. Tung-Yi Lin*, Ai-Jung Tseng, Wei-Lun Qiu, Chi-Hsein Chao, Mei-Kuang Lu. A sulfated glucan from Antrodia cinnamomea reduces Slug expression through regulation of TGFβ/AKT/GSK3β axis in lung cancer. Carbohydrate Polymers. 2019. 210:175-184. (SCI, IF: 11.2, Rank: 3.5%) First & Corresponding author
6. Mei-Kuang Lu*, Tung-Yi Lin*, and Chia-Chuan Chang. Chemical identification of a sulfated glucan from Antrodia cinnamomea and its anti-cancer functions via inhibition of EGFR and mTOR activity. Carbohydrate Polymers. 2018. 202:536-544. (SCI, IF: 11.2, Rank: 3.5%) Co-first author
7. Tung-Yi Lin*, Ai-Jung Tseng, Chi-Hsein Chao, Mei-Kuang Lu. Microelements induce changes in characterization of sulfated polysaccharides from Antrodia cinnamomea. International Journal of Biological Macromolecules. 2018. 120:952-958. (SCI, IF: 8.2, Rank: 5.8%) First & Corresponding author
8. Mei-Kuang Lu*, Tung-Yi Lin*, Chun-Hao Hu, Chi-Hsein Chao, Chia-Chuan Chang, and Hsien-Yeh Hsu. Characterization of a sulfated galactoglucan from Antrodia cinnamomea and its anticancer mechanism via TGFβ/FAK/Slug axis suppression. Carbohydrate Polymers. 2017. 167: 229–239. (SCI, IF: 11.2, Rank: 3.5%) Co-first author
9. Mei-Kuang Lu*, Tung-Yi Lin*, Chi-Hsein Chao, Chun-Hao Hu and Hsien-Yeh Hsu. Molecular mechanism of Antrodia cinnamomea Sulfated polysaccharide on the suppression of lung cancer cell growth and migration via induction of transforming growth factor β receptor degradation. International Journal of Biological Macromolecules. 2017. 95:1144–1152. (SCI, IF: 8.2, Rank: 5.8%) Co-first author

➤Papers-Blown seaweed Polysaccharides (Fucoidan)

1. Tung-Yi Lin*, Hung-Chih Lo, Wei-Lun Qiu, Chi-Hsein Chao, Mei-Kuang Lu, and Hsien-Yeh Hsu. Biochemical characterization and anti-cancer activity of tangential flow filtration system assisted purification of fucoglucan from Laminaria japonica. International Journal of Biological Macromolecules. 2023. 227:1-9. (SCI, IF: 8.2, Rank: 5.8%) First & Corresponding author
2. Wei-Lun Qiu, Ai-Jung Tseng, Hsien-Yeh Hsu, Wei-Hung Hsu, Zhi-Hu Lin, Wei-Jyun Hua, Tung-Yi Lin*. Fucoidan increased the sensitivity to gefitinib in lung cancer cells correlates with reduction of TGFβ-mediated Slug expression. International Journal of Biological Macromolecules. 2020. 153:796-805. (SCI, IF: 8.2, Rank: 5.8%) Corresponding author
3. Hsien-Yeh Hsu*, Tung-Yi Lin*, Chun-Hao Hu, David Ta Fu Shu, Mei-Kuang Lu. Fucoidan Upregulates TLR4/CHOP-Mediated Caspase-3 and PARP Activation to Enhance Cisplatin-Induced Cytotoxicity in Human Lung Cancer Cells. Cancer Letters. 2018. 432:112-120. (SCI, IF: 9.7, Rank: 14.1%) Co-first author
4. Hsien-Yeh Hsu*, Tung-Yi Lin*, Shu-Ming Tsao, Mei-Kuang Lu, Pei-Ju Leng, and Yu-Chung Wu. Fucoidan induces Toll-like receptor 4-regulated reactive oxygen species and promotes endoplasmic reticulum stress-mediated apoptosis in lung cancer. Scientific Reports. 2017. 7:44990. (SCI, IF: 4.6, Rank: 30.1%) Co-first author
5. Hsien-Yeh Hsu*, Tung-Yi Lin*, Yu-Chung Wu, Shu-Ming Tsao, Pai-An Hwang, Yu-Wei Shih and Jason Hsu. Fucoidan inhibition of lung cancer in vivo and in vitro: role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation. Oncotarget. 2014. 5(17):7870-85. (SCI) Co-first author
6. Hsien-Yeh Hsu*, Tung-Yi Lin*, Pai-An Hwang, Ling-Ming Tseng, Ren-Hao Chen, Shu-Ming Tsao and Jason Hsu. Fucoidan induces changes in the epithelial-mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer. Carcinogenesis. 2013. 34(4):874-84. (SCI, IF: 4.7, Rank: 35.3%) Co-first author

➤Papers-Polysaccharides from various natural products

1. Leonel Pereira, Chia-Chuan Chang, Jianxun Ding, Tung-Yi Lin and Zhong Liu. The polysaccharides from marine organisms and fungi: Biological functions and molecular mechanisms. Frontiers in Pharmacology. 2022. 13:1085346. (SCI, IF: 5.6, Rank: 16.2%)
2. Tung-Yi Lin, Mei-Kuang Lu, Chia-Chuan Chang*. Structural identification of a fucose-containing 1,3-β-mannoglucan from Poria cocos and its anti-lung cancer CL1-5 cells migration via inhibition of TGFβR-mediated signaling. International Journal of Biological Macromolecules. 2020. 157:311-318. (SCI, IF: 8.2, Rank: 5.8%) First author

➤Papers-Herbal Formula and small compounds

1. Chung-Ting Kao, Fan-Wei Yang, Meng-Chen Wu, Tzu-Huan Hung, Chen-Wei Hu, Chiu-Hua Chen, Pin-Chien Liou, Te-Lun Mai, Chia-Chih Chang, Tung-Yi Lin, Ying-Lan Chen*, Ying-Chung Jimmy Lin*, Jung-Chen Su*. Systematic synthesis and identification of monolignol pathway metabolites. New Phytologist. 2024. (SCI, IF: 8.3, Rank: 4.2%)
2. Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Ling Yang, Tung-Yi Lin, Muh-Hwa Yang, Tung-Hu Tsai*. Transporter modulation of molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-brain barrier in a rat. Communications medicine. 2023. 3: 150. (SCI)
3. Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Tung-Yi Lin, Muh-Hwa Yang, Jeffrey W. Dalley, Tung-Hu Tsai*. Transfer and biotransformation of the COVID-19 prodrug molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-placenta barrier. 2023. 95: 104748. (SCI, IF: 11.1, Rank: 7.4%)
4. Yong-Hong Yang, Che-Sheng Wen, Yung-Ling Kuo, Su-Ling Fu, Tung-Yi Lin, Chao-Ming Chen, Po-Kuei Wu, Wei-Ming Chen, Jir-You Wang. GuiLu-ErXian Glue extract promotes mesenchymal stem cells (MSC)-Induced chondrogenesis via exosomes releases and delays aging in the MSC senescence process. Journal of Ethnopharmacology. 2023. 317: 116784. (SCI, IF: 5.4, Rank: 12.2%)
5. Chueh-Tan Chen, Chian-Feng Chen, Tung-Yi Lin, Wei-Jyun Hua, Kate Hua, Ching-Yao Tsai*, Chung-Hua Hsu*. Traditional Chinese medicine Kuan-Sin-Yin decoction inhibits cell mobility via downregulation of CCL2, CEACAM1 and PIK3R3 in hepatocellular carcinoma cells. Journal of Ethnopharmacology. 2023. 317:114636. (SCI, IF: 5.4, Rank: 12.2%) Third author
6. Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Tung-Yi Lin, Muh-Hwa Yang, Jeffrey W. Dalley, Tung-Hu Tsai*. Biotransformation and brain distribution of the anti-COVID-19 drug molnupiravir and herb-drug pharmacokinetic interactions between the herbal extract Scutellaria formula-NRICM101. Journal of Pharmaceutical and Biomedical Analysis. 2023. 234:115499. (SCI, IF: 3.4, Rank: 34.9%)
7. Yueh-Hsin Ping, Hsin Yeh, Li-Wei Chu, Zhi-Hu Lin, Yin-Chieh Hsu, Lie-Chwen Lin, Chung-Hua Hsu, Shu-Ling Fu, Tung-Yi Lin*. The Traditional Chinese Medicine Formula Jing Guan Fang for preventing SARS-CoV-2 infection: from clinical observation to basic research. Frontiers in Pharmacology. 2022. 13:744439. (SCI, IF: 5.6, Rank: 16.2%) Corresponding author
8. Kai-Wei Chang, Tung-Yi Lin, Shu-Ling Fu, Yueh-Hsin Ping, Fen-Pey Chen, Yen-Ying Kun*. A Houttuynia Cordata-based Chinese herbal formula improved symptoms of allergic rhinitis during COVID-19 pandemic. Journal of the Chinese Medical Association. 2022. 85(6):717-722. (SCI, IF: 3.396, Rank: 41.3%) Second author
9. Zhi-Hu Lin, Jinsong Hu, Huagang Shi, Chia-Ching Liaw, Wei-Lun Qiu, Wei-Hung Hsu, Tung-Yi Lin*. Water extract of medicinal ink (WEMI) attenuates lipopolysaccharide-induced NO production of Raw264. 7 cells via downregulation JAK2/STAT3-mediated iNOS expression. Journal of Ethnopharmacology. 2022. 282:114636. (SCI, IF: 5.4, Rank: 12.2%) Corresponding author

➤Papers-Biomedical Engineering

1. Yi-Hong Lin, Chih-Ning Tsai, Po-Feng Chen, Yen-Tzu Lin, Sorour Darvishi, Hubert H. Girault, Tung-Yi Lin, Mei-Yi Liao, and Tzu-En Lin*. AI-Assisted Fusion of Scanning Electrochemical Microscopy Images Using Novel Soft Probe. ACS Measurement Science Au. 2022. 2(6): 576–583. (SCI)
2. Tzu-En Lin, Ming-Chun Chien, Po-Feng Chen, Pei-Wen Yang, Huai-En Chang, Ding-Han Wang, Tung-Yi Lin, and Yung-Jung Hsu. A Sensor-Integrated Face Mask Using Au@SnO₂ Nanoparticle Modified Fibers and Augmented Reality Technology. ACS Omega. 2022. 7:42233-42241. (SCI, IF: 4.1, Rank: 38.8%)
3. Wei-Shan Hsu, Anant Preet, Tung-Yi Lin and Tzu-En Lin*. Miniaturized Salinity Gradient Energy Harvesting Devices. Molecules. 2021, 26(18): 5469. (SCI, IF: 4.6, Rank: 34.0%) Third author
4. Tung-Yi Lin, Kuan-Yi Lee, Tsui-Ling Chang, Chia-Chin Chang, Yen-Zhu Lin. The electrochemical method for detecting 26S proteasome. Sensors and Actuators B-Chemical. 2011. 160:412-417. (SCI, IF: 8.4, Rank: 1.6%) First author
5. Tung-Yi Lin, Kuan-Yi Lee, Tsui-Ling Chang and Chia-Chin Chang. The electrolyte effect on adsorption of 1,6-Hexanedithiol at gold electrode. National University of Tainan, Journal of Ecology and Environmental Sciences. 2010. 3(1): 32-45. First author

➤Papers-Sport Science

1. Yun-Tsung Chen, Yao-Yi Hsieh, Jen-Yu Ho, Chien Chang Ho, Tung-Yi Lin* and Jung-Charng Lin. Running interval training combined with blood flow restriction increases maximal running performance and muscular fitness in male runners. Scientific reports. 12:9922. (SCI, IF: 4.996, Rank: 26.0%) Corresponding author
2. Yun-Tsung Chen, Yao-Yi Hsieh, Jen-Yu Ho, Tung-Yi Lin* and Jung-Charng Lin. Two weeks of detraining reduces cardiopulmonary function and muscular fitness in endurance athletes. European journal of sport science. 2022. 22(3):399-406. (SCI, IF: 3.980, Rank: 27.6%) Corresponding author
3. Yun-Tsung Chen, Yao-Yi Hsieh, Jen-Yu Ho, Tung-Yi Lin and Jung-Charng Lin. Running training combined with blood flow restriction increases cardiopulmonary function and muscle strength in endurance athletes. Journal of strength and conditioning research. 2022. 36(5):1228-1237. (SCI, IF: 4.415, Rank: 20.7%)

Conference:

1. Zhi-Hu Lin, Hsin Yeh, Di Ngoc Kha Vo, Hung-Chih Lo, Wei-Jyun Hua, Ha Phan Thanh Ho, Ming-Han Tsai, Tung-Yi Lin*. Ganoderma microsporum immunomodulatory protein (GMI) prevents spike protein-containing pseudoviruses infection and ameliorates SARS-CoV-2 envelope protein-induced inflammation. The 19^th Meeting of the Consortium for Globalization of Chinese Medicine (NO: 93). Chengdu, China. 2023.
2. Wei-Hung Hsu, Jinsong Hu, Huagang Shi, Zhi-Hu Lin, Wei-Lun Qiu, Chia-Ching Liaw, Tung-Yi Lin*. Medicinal Ink (WEMI) attenuates lipopolysaccharide-induced inflammation and inhibits melanoma cells. The 19^th Meeting of the Consortium for Globalization of Chinese Medicine (NO: 94). Chengdu, China. 2023.
3. Zhi-Hu Lin, Mei-Kuang Lu, Ai-Jung Tseng, Chi-Hsein Chao, Tung-Yi Lin*. Sulfated polysaccharides from Antrodia cinnamomea activates macrophages toward M1 phenotype. International Symposium on Taiwan Medicinal mushrooms: Antrodia cinnamomea (NO: P6). National Biotechnology Research Park, Taiwan. 2022. (Silver medal)
4. Wei-Jyun Hua, Ai-Jung Tseng, Tsung-His Tu, Tung-Yi Lin*. Ganoderma microsporum protein (GMI) exerts anti-motility activity and potentiates temozolomide efficacy via induction of Slug degradation in glioblastoma multiforme cells. The 37^th Symposium on Natural Products (NO: NPB02). Kaohsiung Medical University, Taiwan, 2022. (Poster Presentation Award)
5. Hsin Yeh, Di Ngoc Kha Vo, Zhi-Hu Lin, Ha Phan Thanh Ho, Wei-Jyun Hua, Wei-Lun Qiu, Ming-Han Tsai, Tung-Yi Lin*. GMI, an immunomodulatory protein from Ganoderma microsporum, prevents SARS-CoV-2 Spike-pseudotyped virus infection through inducing ACE2 degradation. The 37th Symposium of Natural Products (NO: NPC02). Kaohsiung Medical University, Taiwan, 2022.
6. Wei-Lun Qiu, Wei-Hung Hsu, Tung-Yi Lin*. A water-soluble glucose-rich polysaccharide from Ganoderma lucidum sensitizes lung cancer cells to cisplatin through inducing apoptosis. The 37^th Symposium of Natural Products (NO: NPA19). Kaohsiung Medical University, Taiwan, 2022. (Poster Presentation Award)
7. Hung-Chih Lo, Hsien-Yeh Hsu, Mei-Kuang Lu, Tung-Yi Lin*. Using Tangential Flow Filtration System to optimize the anti-cancer activity of polysaccharide from Laminaria japonica. The 37^th Symposium of Natural Products (NO: NPA18). Kaohsiung Medical University, Taiwan, 2022.
8. Zhi-Hu Lin, Chia-Ching Liaw, Wei-Lun Qiu, Wei-Hung Hsu and Tung-Yi Lin*. Studies on chemical constituents and anti-inflammation activities of water extract Medicinal Ink (WEMI). The 21st International Congress of International Society for Ethnopharmacology (Ethnopharmacology 2022). (ET034). China Medical University, 2022.
9. Zhi-Hu Lin, Mei-Kuang Lu, Ai-Jung Tseng, Chi-Hsein Chao, and Tung-Yi Lin*. Sulfated polysaccharides from Antrodia cinnamomea inhibits lung cancer cells via induction of apoptosis and activation of macrophages. 14^th Meeting of the Asia Pacific Federation of Pharmacologists. (NO: EO83). Taipei International Convention Center, Taiwan, 2021.
10. Wei-Jyun Hua, Wei-Hung Hsu and Tung-Yi Lin*. Effects of polysaccharide from Ganoderma lucidum on suppressing oral squamous cell carcinoma growth by regulating EGFR/AKT signaling and induction of apoptosis. The 36^th Symposium of Natural Products (NO: NPC04). National Sun Yat-sen University, Taiwan, 2021.
11. Wei-Lun Qiu, Chuang-Ching Chen, and Tung-Yi Lin*. Anti-colon cancer effect of Ganoderma microsporum immunomodulatory protein combined with 5-Flurouracie. The 36^th Symposium of Natural Products (NO: PHA07). National Sun Yat-sen University, Taiwan, 2021.
12. Zhi-hu Lin, Chia-Ching Liaw, Wei-Lun Qiu, Wei-Hung Hsu and Tung-Yi Lin*. Water extract of medicinal ink (WEMI) presents anti-inflammatory effects on LPS-induced Raw264.7 cells via regulation of JAK2/STAT3 signaling pathway. The 36^th Symposium of Natural Products (NO: TCM25). National Sun Yat-sen University, Taiwan, 2021.
13. Li-Chen Huang, Wei-Jyun Hua and Tung-Yi Lin*. GMI induces proteasome-dependent PD-L1 degradation via regulating GSK3β pathway in lung cancer cells. The 36^th Symposium of Natural Products (NO: PHA18). National Sun Yat-sen University, Taiwan, 2021.
14. Zhi-hu Lin, Wei-Hung Hsu, and Tung-Yi Lin*. The anti-inflammatory effects of Jinchuang Ointment on LPS-induced Raw 264.7 cells. The 35^th Symposium of Natural Products (NO: C-05). Taipei Medical University, Taiwan, 2020.
15. Tung-Yi Lin* and Mei-Kuang Lu. Squalene induces changes in biochemical characterization of polysaccharides from Antrodia cinnamomea. The 35^th Symposium of Natural Products (NO: C-08). Taipei Medical University, Taiwan, 2020.
16. Hsin Yeh, Wei-Jyun Hua, and Tung-Yi Lin*. Fungal immunomodulatory proteins downregulate expression of heat shock proteins in lung carcinoma LLC1 cells. The 35^th Symposium of Natural Products (NO: B-22). Taipei Medical University, Taiwan, 2020.
17. Wei-Hung Hsu, Wei-Lun Qiu, Chung-Hua Hsu, Tung-Yi Lin*. Characterization of a glucose-rich polysaccharide from Ganoderma lucidum on suppression of lung cancer and enhancement of cisplatin-induced cytotoxicity.12^th Taipei Traditional Chinese Medicine International Forum 2020 (NO: TICMIF-2020-PO42). NTUH International Convention Center, Taiwan, 2020.
18. Wei-Lun Qiu and Tung-Yi Lin*. Fucoidan suppressed TGFβ-mediated molecules correlated with the sensitive enhancement of gefitinib in lung cancer cells. The 35^th Symposium of Natural Products (NO: B-10). Taipei Medical University, Taiwan, 2020.
19. Tung-Yi Lin* and Mei-Kuang Lu. Sulfated polysaccharides from Antrodia cinnamomea cultured with Sodium thiosulfate enhanced synergistically clinical drug-induced cytotoxic effects in TKI-resistant lung cancer H1975 cells. The 34^th Symposium of Natural Products (NO: NPP-36). Chang Gung University of Science and Technology, Taiwan, 2019.
20. Tung-Yi Lin, Mei-Kuang Lu and Chia-Chuan Chang. Mannoglucan from Poria cocos and its anti-cancer related activities. The 34^th Symposium of Natural Products (NO: NPC-22). Chang Gung University of Science and Technology, Taiwan, 2019.
21. Ai-Jung Tseng, Tsung-His Tu and Tung-Yi Lin*. GMI, a protein from Ganoderma microsporum, suppresses cell viability and migration via inhibition of EGFR-mediated signaling in glioblastoma multiforme GBM8401 cells. 2019 Southeast Asia Symposium of Traditional Medicine (NO: BR-02), National Yang-Ming University, Taiwan, 2019.
22. Wei-Jyun Hua and Tung-Yi Lin*. Fungal immunoregulatory protein, GMI, suppresses cell viability and mobility in lung squamous carcinoma cells. 2019 Southeast Asia Symposium of Traditional Medicine (NO: BR-15), National Yang-Ming University, Taiwan, 2019. (Excellent Poster Award)
23. Tung-Yi Lin*, Mei-Kuang Lu. A sulfated glucan from Antrodia cinnamomea suppresses lung cancer: blockage of TGFβ-mediated signalings controls Slug stability. The 33th Symposium of Natural Products (NO: NP-8). Kaohsiung Medical University, Taiwan,
24. 林東毅、李冠誼、張家欽、張翠玲。26S proteasome偵測系統中電解液對於黃金電極吸附HDT影響之研究。中國材料年會 (論文編號: 06-0612)，國立東華大學，2009。

Patents and know-how:

1. Hsien-Yeh Hsu and Tung-Yi Lin. Method for treating a refractory or relapsed lung cancer. US 9,827,288 B2. 2017. (徵求技術轉移)
2. Tung-Yi Lin and Mei-Kuang Lu. Composition and method for preventing or treating cancer. Provisional application: 63/283,420. 2021. (徵求技術轉移或讓與)
3. Chung-Hua Hsu, Shu-ling Fu, Tung-Yi Lin, Yueh-Hsin Ping. Herbal composition, preparation method thereof and method for preventing or treating respiratory disorder by administering the same. Provisional application: 63/280,635. 2021. (徵求技術轉移或讓與)
4. Tung-Yi Lin and Ming-Han Tsai. An Immunomodulatory protein for prevention and/or treatment of coronavirus infection. Provisional application: 63/266,712. 2022. (徵求技術轉移)
5. Tung-Yi Lin. An Immunomodulatory protein for alleviation and/or treatment of coronavirus disease. Provisional application: 63/266,716. 2022. (徵求技術轉移)
6. Tung-Yi Lin. Method for treating PD-L1 expressing cancer. Provisional application: 63/303,523. 2022. (徵求技術轉移或讓與)